Studies

CellWell record HH-79645

Jellyfish collagen ameliorates collagen-induced arthritis CIA in Sprague Dawley rats by modulating inflammatory mediators by inhibiting the NF κB and JAK STAT pathways

Mona Assas; Amal Shams; Abdallah S Salah; Mohamed M Zayed; Ayman Atiba; Doaa H Assar; Rasha A Al Wakeel; Alaa Elgaabari; Zizy I Elbialy

2025

In plain language

In 28 male Sprague Dawley rats with collagen-induced arthritis, oral jellyfish collagen, best at 100 ug/kg, downregulated NF-kB, IL-1beta, TNF-alpha, COX-2, JAK1 and STAT3 while upregulating TGF-beta and IL-10.

Evidence
Emerging

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