Studies

CellWell record HH-79118

Complement blockade: Therapeutic promises and remaining challenges in clinical practice

Gema Fernández-Juárez; Javier Azores-Moreno; Lina León-Machado; Irene Vázquez-Raso; María Soriano-Guillén; Ana Mendoza; María Maldonado; Begoña Rivas Becerra; Cristina Vega Cabrera; Amir Shabaka

2026

In plain language

A review reports C5 blockade with eculizumab improved renal function and survival in atypical hemolytic uremic syndrome, but heterogeneity of complement dysregulation across glomerulopathies limits a uniform therapeutic strategy.

Evidence
Emerging

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