CellWell record HH-79117
Complement and inflammasome crosstalk in chronic inflammation
Larisa Janžič; Katarina Kouter
2026
In plain language
A review details how complement components C3a, C5a and the membrane attack complex prime NLRP3 inflammasome activation while IL-1beta and IL-18 feed back to enhance complement, forming self-amplifying loops in chronic disease.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-79117
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