CellWell record HH-79012
Microglia-Specific K2P Channel THIK-1: Structure, Function, and Therapeutic Potential
Yoonsub Kim; Bo Hyun Lee; Byeonggyu Ahn; Eun-A Ko; Dawon Kang
2026
In plain language
A review describes THIK-1 as a microglia-enriched two-pore potassium channel whose potassium efflux is required for NLRP3 inflammasome activation, surveillance motility and synaptic pruning.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-79012
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