CellWell record HH-78993
Oncogenic receptor tyrosine kinase signaling is driven by the Golgi protein GOLPH3 and its interaction with MYO18A
Kyle A Starost; Jagadeeswara R Bommi; Marshall C Peterman; Mengke X McCullough; Matthew D Buschman; Bahda Yun; Seth J Field
2026
In plain language
GOLPH3 increased delivery of receptor tyrosine kinases to the plasma membrane and amplified all downstream signalling, and this depended on its interaction with myosin 18A at the Golgi.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-78993
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