Studies

CellWell record HH-78156

Synergistic antibacterial effect and mechanism of benzalkonium chloride and polymyxin B against Pseudomonas aeruginosa

Wang C; Zhang J; Li T; Wang J; Xu D; Ma Q

Journal of environmental sciences (China) ยท 2026

In plain language

Combining benzalkonium chloride with polymyxin B was synergistic against Pseudomonas aeruginosa, disrupting the cell envelope and membrane potential, downregulating lipid A modification genes, raising reactive oxygen species and lowering ATP synthesis.

Evidence
Emerging

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-78156

Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.