CellWell record HH-78142
N-Aryl-S-aryl-2-mercaptoacetamide Derivatives Effectively Inhibit Mushroom and Cellular Tyrosinase Activities, Melanin Production, and Pigmentation in Zebrafish Larvae: Regarding Copper Ion Chelation
Hee Jin Jung; Hye Jin Kang; Hyeon Seo Park; Minchang Kim; Hyunju Lee; Hyunhee Ju; Yeonsoo Jeong; Yujin Park; Hae Young Chung; Hyung Ryong Moon
2026
In plain language
Among 11 mercaptoacetamide derivatives, copper-chelating ability did not predict tyrosinase inhibition; three inhibited cellular tyrosinase in B16F10 cells better than kojic acid and one suppressed pigmentation in zebrafish larvae.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-78142
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