CellWell record HH-77377
Investigation of the Enhancement Effect of Evodia rutaecarpa Volatile Oil on Transdermal Delivery of Total Glucosides of Paeony: Mechanistic Insight Based on Interactions Among Drug, Enhancer, and Skin
Zhanghong Yao; Fei Song; Yan Liang; Yunfeng Liu; Weifeng Zhu; Yongmei Guan; Lili Liu
2026
In plain language
Evodia rutaecarpa volatile oil increased transdermal permeation of total glucosides of paeony in a concentration-dependent way in rat skin, by disrupting intercellular lipids, downregulating claudin-1, claudin-7 and occludin, and improving local microcirculation.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-77377
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