CellWell record HH-76689
Comparative effects of salt substitutes on blood pressure, cardiovascular events and mortality: a systematic review and network meta-analysis
Honghao Lai; Gihad Nesrallah; Gordon H Guyatt; Robin W M Vernooij; Jiayi Liu; Weilong Zhao; Liangying Hou; Bei Pan; Jiajie Huang; Norm R C Campbell; Jinhui Tian; Kehu Yang; Long Ge; Bradley C Johnston
2026
In plain language
Pooling 34 randomised trials in 37,063 adults, moderate-potassium low-sodium salt substitutes lowered systolic blood pressure 4.39 to 4.64 mmHg and mortality by 7-17 deaths per 1,000, but one Chinese trial drove the mortality result.
- Evidence
- Established
Cite this record: https://thecellwell.org/studies/HH-76689
Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.
This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.