CellWell record HH-76489
Molecular Determinants of Ribosome Binding for the Antimicrobial Peptide Pdi1
Trevor T Dean; Alyah Ziyad; Dorota Klepacki; José A Villegas; Terry W Moore
2026
In plain language
Biolayer interferometry showed the proline-rich antimicrobial peptide Pdi1 dissociates slowly from the ribosome, and alanine substitutions at specific C-terminal residues reduced both binding and antibacterial activity.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-76489
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