Studies

CellWell record HH-76380

Lim Homeobox 8 Is Essential for Beta Adrenergic Stimulation of Thermogenesis in Human Adipocytes

Katalin Gyurina; Ádám Radványi; László Sasi-Szabó; Enikő Felszeghy; Emese Rácz; Gábor Méhes; Andrea Kádár; Csaba Fekete; Tamás Röszer

2026

In plain language

LHX8 was required for beta-adrenergic thermogenesis in human and mouse adipocytes, its expression fell with pediatric obesity, and overexpression enhanced thermogenesis via adipocyte interleukin-33.

Evidence
Emerging

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