CellWell record HH-76297
Dysbiosis in the Gut-Liver Axis Is Associated With Low Bone Mass During Murine Cholestasis
Brooke Hutchison; Jamie Fornsaglio; Ridgeway Case; Pam Cornuet; Fu-Ying Qin; Xiaochao Ma; Kari Nejak-Bowen; Matthew D Carson
2026
In plain language
Mice given a cholestasis-inducing diet from 11 to 15 weeks lost bone mass through more osteoclasts and fewer osteoblasts, and their bone marrow bile acids suppressed osteoblastogenesis in culture.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-76297
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