CellWell record HH-74863
Pyruvate Dehydrogenase Complex Deficiency: A Review of Treatments and Case Series
Batya Betesh-Abay; Eilon Shany; Orna Staretz-Chacham; Ilan Shelef; Abed N Azab
2026
In plain language
Scoping review of 7 preclinical and 10 human studies plus three patient cases found dichloroacetate and the ketogenic diet were the most studied treatments for pyruvate dehydrogenase complex deficiency, with reduced lactate reported.
- Evidence
- Emerging
Cite this record: https://thecellwell.org/studies/HH-74863
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