CellWell record HH-73420
Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial
Rynne J; Mosavie M; Masse MH; Ménard J; Battista MC; Maslove DM; Del Sorbo L; St-Arnaud C; DAragon F; Fox-Robichaud A; Charbonney E; Adhikari NKJ; Lamontagne F; Shankar-Hari M; LOVIT Investigators, the Canadian Critical Care Trials Group
Intensive care medicine · 2025
In plain language
In 457 adults with sepsis from the LOVIT trial, intravenous vitamin C produced no discernible change in 26 plasma inflammation markers, and no clustered subtype benefited; the odds ratios varied only in the magnitude of harm.
- Evidence
- Established
- Design
- Randomized controlled trial
Cite this record: https://thecellwell.org/studies/HH-73420
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