CellWell record HH-73363
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial
Sevransky JE; Rothman RE; Hager DN; Bernard GR; Brown SM; Buchman TG; Busse LW; Coopersmith CM; DeWilde C; Ely EW; Eyzaguirre LM; Fowler AA; Gaieski DF; Gong MN; Hall A; Hinson JS; Hooper MH; Kelen GD; Khan A; Levine MA; Lewis RJ; Lindsell CJ; Marlin JS; McGlothlin A; Moore BL; Nugent KL; Nwosu S; Polito CC; Rice TW; Ricketts EP; Rudolph CC; Sanfilippo F; Viele K; Martin GS; Wright DW; VICTAS Investigators
JAMA ยท 2021
In plain language
In 501 adults with sepsis, intravenous vitamin C, thiamine and hydrocortisone every six hours found no difference in ventilator and vasopressor-free days versus placebo, median 25 versus 26 days; the trial stopped early for funding.
- Evidence
- Established
- Design
- Randomized controlled trial
Cite this record: https://thecellwell.org/studies/HH-73363
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