Studies

CellWell record HH-73360

A randomized trial of pharmacological ascorbate, gemcitabine, and nab-paclitaxel for metastatic pancreatic cancer

Bodeker KL; Smith BJ; Berg DJ; Chandrasekharan C; Sharif S; Fei N; Vollstedt S; Brown H; Chandler M; Lorack A; McMichael S; Wulfekuhle J; Wagner BA; Buettner GR; Allen BG; Caster JM; Dion B; Kamgar M; Buatti JM; Cullen JJ

Redox biology ยท 2024

In plain language

In 34 adults with metastatic pancreatic cancer, intravenous vitamin C at 75 g three times weekly alongside gemcitabine and nab-paclitaxel raised serum ascorbate to millimolar and median survival to 16 from 8.3 months, reported with 90 percent confidence intervals.

Evidence
Established
Design
Randomized controlled trial

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