CellWell record HH-64472
Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets
Xingpeng Di; Xiaoshuai Gao; Liao Peng; Jianzhong Ai; Xi Jin; Shiqian Qi; Hong Li; Kunjie Wang; Deyi Luo
Signal Transduction and Targeted Therapy ยท 2023
In plain language
A review of how cells convert mechanical cues, pressure, shear, stiffness and fluid viscosity, into biochemical signals through Piezo channels, integrins, YAP/TAZ and TRPV4, and how sustained mechanical stress is linked to fibrosis and tumour growth.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-64472
Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.
This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.