Studies

CellWell record HH-618469

Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial

Buys SS; Partridge E; Black A; Johnson CC; Lamerato L; Isaacs C; Reding DJ; Greenlee RT; Yokochi LA; Kessel B; Crawford ED; Church TR; Andriole GL; Weissfeld JL; Fouad MN; Chia D; O'Brien B; Ragard LR; Clapp JD; Rathmell JM; Riley TL; Hartge P; Pinsky PF; Zhu CS; Izmirlian G; Kramer BS; Miller AB; Xu JL; Prorok PC; Gohagan JK; Berg CD; PLCO Project Team

JAMA ยท 2011

In plain language

In this randomized trial of 78,216 US women aged 55-74, annual CA-125 and transvaginal ultrasound screening over 13 years did not lower ovarian cancer mortality versus usual care, and false-positive results led to serious surgical complications; funding not stated.

Evidence
Established

Read it on PubMed

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