Studies

CellWell record HH-618452

50th anniversary of the first clinical trial with ICI 46,474 (tamoxifen): then what happened?

Jordan VC

Endocrine-related cancer ยท 2021

In plain language

This review traces ICI 46,474, first investigated for fertility control, to its later clinical use as a breast cancer drug, which a 1971 trial showed active versus alternatives.

Evidence
Emerging
Design
Expert review

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