CellWell record HH-615391
Hypertonic saline and heart failure: "sodium-centric" or "chlorine-centric"?
Mazón-Ruiz J; Romero-González G; Sánchez E; Banegas-Deras EJ; Salgado-Barquinero M; la Varga LG; Bande-Fernández JJ; Gorostidi M; Alcázar R
Nefrologia · 2024
In plain language
This review proposes that chloride deficit, rather than sodium alone, may be the main driver of plasma volume changes with hypertonic saline plus loop diuretics in heart failure, suggesting chloride-correcting strategies.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-615391
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