Studies

CellWell record HH-609583

Inflammation-triggered nanodrug delivery microneedles targeting pathogenic COX2+ endothelial cell-mediated glycocalyx degradation to ameliorate psoriasis

Zelin Ou; Keyi Zou; Linxi Zeng; Jingyi Wang; Huan Yang; Yuting Cao; Shuhan Wei; Yue Li; Yunxuan Zhang; Haibo Wang; Hua Wang; Bibo Ren; Xiaoyan Luo

2027

In plain language

In psoriasis-related experiments, a microneedle platform delivering an anthelmintic drug increased endothelial glycocalyx coverage from 11.9% to 87.5% and reduced immune cell infiltration.

Evidence
Emerging
Design
Primary research (design unspecified)

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