CellWell record HH-5868
Changes in 2-hydroxyestrone and 16alpha-hydroxyestrone metabolism with flaxseed consumption: modification by COMT and CYP1B1 genotype
McCann SE, Wactawski-Wende J, Kufel K, Olson J, Ovando B, Kadlubar SN, Davis W, Carter L, Muti P, Shields PG, Freudenheim JL
Cancer Epidemiol Biomarkers Prev ยท 2007
In plain language
One week of daily flaxseed intake raised the ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone in urine. The increase was significantly greater in people with more CYP1B1 variant alleles, while a similar trend for COMT genotype was not statistically significant.
- Evidence
- Emerging
- Design
- Clinical trial
Cite this record: https://thecellwell.org/studies/HH-5868
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