CellWell record HH-586602
Integrative serum metabolite prioritization and functional screening identify N-acetyl-L-glutamine as a protective candidate in premature ovarian insufficiency
Xinyue Zhang; Chen Chen; Xiaolan Zhu
2026
In plain language
Mendelian randomization linked sphinganine-1-phosphate to higher premature ovarian insufficiency risk, and N-acetyl-L-glutamine reduced senescence, oxidative stress and mitochondrial dysfunction in cyclophosphamide-injured granulosa-like cells.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-586602
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