CellWell record HH-582723
Targeting DNGR-1 with Fangchinoline Elevates Dendritic Cell Antigen Cross-Presentation-Mediated Antitumor Immunity in Melanoma
Liao Y; Ren Z; Zhou J; Luo H; Li Y; Chen D; Jiang Y; Li C; Zheng M; Li A; Wang Y; Zhang Y; Wang D; Jiang Y; Gu J; Du B; Shi Y; Liu F; Xiao J; Wang K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ยท 2026
In plain language
Fangchinoline, a natural alkaloid, was found to enhance dendritic cell antigen cross-presentation via DNGR-1 and to synergize with PD-1 blockade in mouse melanoma models.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-582723
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