Studies

CellWell record HH-565193

Immune-Mediated Colitis Induced by Immune Checkpoint Inhibitors: Pathophysiology, Clinical Management, and the Emerging Role of Fecal Microbiota Transplantation

Zeljka Belosic Halle; Vedran Tomasic; Alen Biscanin; Petra Cacic; Ivona Saric; Sanda Mustapic; Josip Stojic; Kresimir Luetic; Dinko Bekic; Matej Paic; Domagoj Micetic; Irena Krznaric Zrnic; Ivna Olic; Melanija Razov Radas; Iva Skocilic; Marin Golčic; Laura Rados; Jasna Radic; Juraj Prejac; Ivana Mikolasevic

2026

In plain language

This review found corticosteroids remain first-line therapy for immune checkpoint inhibitor-induced colitis, with infliximab and vedolizumab effective in steroid-refractory cases and fecal microbiota transplantation showing promise in refractory disease.

Evidence
Emerging
Design
Expert review

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