CellWell record HH-5575
Fast and slow voltage-dependent dynamics of magnesium block in the NMDA receptor: the asymmetric trapping block model
Kampa BM, Clements J, Jonas P, Stuart GJ
J Neurosci ยท 2004
In plain language
Extracellular magnesium ions block the NMDA receptor channel in a voltage-dependent manner, only releasing the channel when the neuron depolarizes, making magnesium a direct electrical gatekeeper of this receptor.
- Evidence
- Established
- Studied in
- Animal, Cell / in vitro
Cite this record: https://thecellwell.org/studies/HH-5575
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