Studies

CellWell record HH-554190

Differentiating mpox infection and vaccination using a validated multiplex orthopoxvirus IgG serology assay

Reed JC; Downs C; McAllister K; Mauer C; McClurkan CL; Wilson D; Holzhauer K; Dickerson JA; Cannon CA; Babu TM; Golden MR; Koelle DM; Greninger AL

Journal of clinical microbiology ยท 2026

In plain language

An antibody ratio of MPXV A35R to VACV A33R orthologs distinguished prior mpox infection from vaccinia vaccination with an AUC of 0.97 in this serology study.

Evidence
Emerging
Design
Technology-validation study

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