CellWell record HH-55208
Associations of social isolation and loneliness with neurological disorders, psychiatric disorders, brain structures and behavioural phenotypes among UK Biobank participants
Zhao YL; Zhang DD; Gao PY; Fu Y; Ge YJ; Chi HC; Guo ZX; Yu HH; Feng JF; Tan L; Cheng W; Zhang YR; Yu JT
Nature communications ยท 2026
In plain language
In over 383,000 UK Biobank participants, social isolation and loneliness were linked to 11 neurological and psychiatric conditions, including depression, dementia and stroke, with genetic evidence supporting causal links to several.
- Evidence
- Emerging
- Design
- Cohort study
Cite this record: https://thecellwell.org/studies/HH-55208
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