CellWell record HH-5503
The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors
Alexeev M, Grosenbaugh DK, Mott DD, Fisher JL
Neuropharmacology ยท 2012
In plain language
In receptor-expression studies, honokiol and magnolol directly enhanced GABA-A receptor currents at synaptic and extrasynaptic sites, a mechanism consistent with calming and sedative effects.
- Evidence
- Emerging
- Studied in
- Human, Animal
Cite this record: https://thecellwell.org/studies/HH-5503
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