Studies

CellWell record HH-549619

Quantitative and qualitative differences in anti-Envelope IgG-secreting cells distinguish subclinical and hospitalized dengue in a Cambodian pediatric cohort

Amandine Trouchet; Sokchea Lay; Matteo Broketa; Pablo Canales-Herrerias; Angga Perima; Bruno Iannascoli; Sotheary Sann; Borita Heng; Sowath Ly; Veasna Duong; Gaël A Millot; Laura Walker; Patrick England; Giovanna Barba-Spaeth; Tineke Cantaert; Pierre Bruhns

2026

In plain language

Hospitalized pediatric dengue patients in Cambodia had fewer IgG-secreting cells and lower-affinity antibodies to the dengue E-dimer than subclinical cases, and quaternary-epitope antibodies appeared only in subclinical cases.

Evidence
Emerging
Design
Primary research (design unspecified)

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