CellWell record HH-5447
Lithium fails to protect dopaminergic neurons in the 6-OHDA model of Parkinson's disease
Yong Y; Ding H; Fan Z; et al.
Neurochemical Research ยท 2011
In plain language
In a rat 6-hydroxydopamine model of Parkinson's disease, lithium treatment did not protect substantia nigra dopaminergic neurons from degeneration, suggesting GSK-3 is only minimally involved in this injury model.
- Evidence
- Emerging
- Studied in
- Human, Animal
Cite this record: https://thecellwell.org/studies/HH-5447
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