Studies

CellWell record HH-544270

Exploring the impact of melatonin on cancer-related fatigue: a dose-response meta-analysis with GRADE evidence evaluation

Sajjad Etesamnia; Mahdiyar Nasiraie-Moghadam; Pariya Mostafazadeh; Mohammad-Reza Jowshan; Kamran Roudini; Seyed Rohollah Miri; Alireza Jahan-Mihan; Alireza Haghighi; Soraiya Ebrahimpour-Koujan

2026

In plain language

Meta-analysis of 12 randomized placebo-controlled trials (1,977 cancer patients) found melatonin was associated with reduced fatigue, with greater benefit at 5-15 mg/day and short-term use.

Evidence
Established
Design
Meta-analysis

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