CellWell record HH-5438
Parkinson's disease: potential actions of lithium by targeting the WNT/beta-catenin pathway, oxidative stress, inflammation and glutamatergic pathway
Vallee A; Vallee JN; Lecarpentier Y
Cells ยท 2021
In plain language
This review proposed that lithium's downregulation of GSK-3beta activates the WNT/beta-catenin pathway, potentially reducing oxidative stress and inflammation relevant to dopaminergic neuron biology in Parkinson's models.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-5438
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