Studies

CellWell record HH-5437

Effects of lithium on cytokine neuro-inflammatory mediators, Wnt/beta-catenin signaling and microglial activation in the hippocampus of chronic mild stress-exposed rats

Habib MZ; Ebeid MA; El Faramawy Y; Saad SST; El Magdoub HM; Attia AA; Aboul-Fotouh S; Abdel-Tawab AM

Toxicology and Applied Pharmacology ยท 2020

In plain language

Chronic lithium reduced hippocampal microglial activation and neuroinflammatory cytokines while enhancing Wnt/beta-catenin signaling in stressed rats, linking anti-inflammatory and neurotrophic pathways in a depression model.

Evidence
Emerging

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