CellWell record HH-5435
Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway
Dong H; Zhang X; Dai X; Lu S; Gui B; Jin W; Zhang S; Zhang S; Qian Y
Journal of Neuroinflammation ยท 2014
In plain language
Lithium suppressed toll-like receptor 4 expression and microglial activation triggered by lipopolysaccharide, acting through the PI3K/Akt/FoxO1 signaling pathway in rodent microglial cell cultures.
- Evidence
- Emerging
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-5435
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