CellWell record HH-5434
Lithium controls central nervous system autoimmunity through modulation of IFN-gamma signaling
Rowse AL; Naves R; Cashman KS; McGuire DJ; Mbana T; Raman C; De Sarno P
PLOS ONE ยท 2012
In plain language
In a mouse model of autoimmune neuroinflammation, lithium reduced STAT1 activation and interferon-gamma signaling in T cells, a distinct cytokine-signaling mechanism separate from its known GSK3 target.
- Evidence
- Emerging
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-5434
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