CellWell record HH-5430
Novel insights into lithium's mechanism of action: neurotrophic and neuroprotective effects
Quiroz JA; Machado-Vieira R; Zarate CA Jr; Manji HK
Neuropsychobiology ยท 2010
In plain language
This review described how lithium raises BDNF and Bcl-2 expression while lowering pro-apoptotic markers, proposing neurotrophic and neuroprotective signaling as a mechanism behind its mood-related benefits.
- Evidence
- Emerging
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-5430
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