CellWell record HH-5427
Inhibition of glycogen synthase kinase 3 by lithium, a mechanism in search of specificity
Chatterjee D; Beaulieu JM
Frontiers in Molecular Neuroscience ยท 2022
In plain language
This review found GSK-3 inhibition remains lithium's best-supported neuropsychiatric mechanism, though whether direct and indirect inhibition pathways are truly specific to lithium's action is still unresolved.
- Evidence
- Contested
- Design
- Expert review
Cite this record: https://thecellwell.org/studies/HH-5427
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