CellWell record HH-5426
A molecular mechanism for the effect of lithium on development
Klein PS; Melton DA
Proceedings of the National Academy of Sciences ยท 1996
In plain language
Lithium directly inhibited glycogen synthase kinase-3 beta in frog and slime-mold development models, identifying GSK-3 inhibition as a core molecular mechanism behind lithium's cellular signaling effects.
- Evidence
- Established
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-5426
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