CellWell record HH-540845
Fasting-mimicking diet induces IFNβ secretion in tumor-associated macrophages via NRF1-mediated ubiquitin-dependent proteolysis of Trex1
Li J; Jiang W; Tu G; Zhong Z; Luo Z; Horng T; Miao C
British journal of cancer · 2026
In plain language
In mouse colon tumor models, fasting-mimicking diet triggered interferon-β secretion in tumor-associated macrophages through NRF1-driven breakdown of Trex1, which contributed to suppressed tumor growth.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-540845
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