Studies

CellWell record HH-540076

Isoflavones impair anti-PD1 efficacy in breast cancer, regardless of dietary fiber or fecal short-chain fatty acid levels

F. de Oliveira Andrade; K. Bouker; Melike Ozgul-Onal; Lu Jin; Idalia Cruz; William G. Helferich; Audrey Gao; Karla A. De Oliveira; Vivek Verma; Christopher Staley; Patricia L Foley; Leena Hilakivi-Clarke

Frontiers in Immunology ยท 2026

In plain language

In C57BL/6 mice with E0771 breast tumors, genistein-supplemented low-fiber chow eliminated anti-PD1 response versus unsupplemented chow; dose and duration not reported, funding not stated.

Evidence
Emerging
Design
Primary research (design unspecified)

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