CellWell record HH-538816
Lentinan inhibits breast cancer cell growth through the dual downregulation of tumor-promoting effectors CD133 and SCGB2A2
Wang J; Cheng H; Mu X; Liu Y; Huang L; Wu N; Zhan Y; Zhang Y; Wang J; Wang K
International journal of biological macromolecules ยท 2026
In plain language
Water-extracted Lentinus edodes polysaccharide suppressed breast cancer growth in vitro and in vivo by downregulating CD133 and SCGB2A2 expression, where it competitively binds CD133 to block its interaction with SCGB2A2.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-538816
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