CellWell record HH-538620
L-Se-methylselenocysteine alleviates iron deposit-induced anxiety- and depression-like behaviors in chronic renal failure rats receiving iron therapy via Nrf2/GPX4 activation
Li F; Liu S; Zhu Y; Shi L; Lv J; Ma S; Xiang S; Hao H; Zhang M; Gu W
Free radical biology & medicine ยท 2026
In plain language
In chronic renal failure rats given iron therapy, L-Se-methylselenocysteine reduced brain iron deposition and anxiety- and depression-like behaviors, accompanied by increased Nrf2 and GPX4, while ESRD patients showed higher depression scores.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-538620
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