Studies

CellWell record HH-537816

Propionate metabolism is dysregulated in non-small cell lung cancer patients and EGFR-mutant drug-tolerant persister cells

Bobak Parang; Liron Yoffe; Rabia Khan; Zhongchi Li; Michal J Nagiec; Eric E Gardner; Yiwey Shieh; Rachel S Heise; Ashish Saxena; Nasser Altorki; John Blenis

2026

In plain language

In non-small cell lung cancer patients, methylmalonic acid was elevated in tumors and serum, and lower MMAB gene expression was linked to its buildup and epithelial-to-mesenchymal transition.

Evidence
Emerging
Design
Primary research (design unspecified)

Read it on PubMed

Powered by CellWell

Cite this record: https://thecellwell.org/studies/HH-537816

Produced by the CellWell Research Engine, custom software owned and operated by CellWell and The Holistic Hub. All rights reserved. This analysis, its indexing and its evidence classifications are proprietary. Any use, republication or onward sharing must credit CellWell Research Engine (thecellwell.org) as the source.

This is an educational research library, not medical advice. Nothing here may be used to diagnose, treat, cure, or prevent any disease. Always consult a qualified professional.