Studies

CellWell record HH-53301

A Meta-Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Cosette A Rhoads; Megan H Hagenauer; Jinglin Xiong; Erin Hernandez; Duy Manh Nguyen; Annaka Saffron; Elizabeth Flandreau; Stanley Watson; Huda Akil

2026

In plain language

In male mice, acute sleep deprivation altered expression of 182 genes in the cerebral cortex, with stress and inflammation pathways up-regulated and vasculature and growth pathways down-regulated.

Evidence
Established
Design
Meta-analysis

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