CellWell record HH-5305
Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein
Eng PH, Cardona GR, Fang SL, Previti M, Alex S, Carrasco N, Chin WW, Braverman LE
Endocrinology ยท 1999
In plain language
In rats, excess iodine exposure triggered a protective drop in sodium-iodide symporter expression, showing that the thyroid's iodine-sensing system actively limits hormone synthesis rather than scaling up with more iodine.
- Evidence
- Established
- Design
- Animal study
- Studied in
- Animal
Cite this record: https://thecellwell.org/studies/HH-5305
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