Studies

CellWell record HH-526288

Bimodal Fluorescent Conjugate Based on Prostate-Specific Membrane Antigen Ligands with the Chelating Agent DOTA and SulfoCy5 Dye: Synthesis, Radiolabeling, and Biological Activity

A. Machulkin; S. A. Petrov; N. S. Butakova; A. S. Lunev; K. A. Petrosova; R. Shafikov; Dmitry A. Skvortsov; I. Mitrofanov; Mariia N. Ivashkovaskaia; E. Beloglazkina; A. A. Larenkov

International Journal of Molecular Sciences ยท 2026

In plain language

A DOTA-linked, SulfoCy5-labeled PSMA ligand conjugate showed tumor-cell visualization comparable to a reference compound and reduced renal accumulation compared with a dye-free conjugate in mice.

Evidence
Emerging
Design
Primary research (design unspecified)

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