CellWell record HH-526172
Adipose triglyceride lipase driven lipolysis as a targetable metabolic vulnerability in prostate cancer with intrinsic metabolic inflexibility
Andreas Tiefenbacher; Madeleine Gudenus; Daniel Valcanover; Barbara Neudert; Raheleh Sheibani-Tezerji; Theresa Mendrina; Jessica Kalla; Laura Pajed; Kristina Draganić; Andrea Haitel; Astrid Haase; Markus Hartenbach; Sazan Rasul; Walter Berger; Rolf Breinbauer; Gernot Grabner; Martina Schweiger; Eva Compérat; Gerda Egger
2026
In plain language
In prostate cancer, PSMA-high tumors showed ATGL upregulation, and ATGL inhibition most strongly reduced proliferation of metabolically inflexible LNCaP cells.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-526172
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