CellWell record HH-507587
Estradiol transdermal spray for menopausal symptom management: From RCT to real-world evidence.
A. L. Hirschberg; P. Stute; F. Águas; T. Fait; P. Polo-Kantola; Fernanda Gobbi Amorim; Ingrid Rézette; P. Hadji
Maturitas · 2026
In plain language
Across an RCT and four real-world studies, estradiol transdermal spray was associated with 70-90% reductions in severe hot flushes and improved sleep, mood and genitourinary symptoms in menopausal women.
- Evidence
- Emerging
- Design
- Primary research (design unspecified)
Cite this record: https://thecellwell.org/studies/HH-507587
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