CellWell record HH-50674
PROVIT-CLOCK: A Potential Influence of Probiotics and Vitamin B7 Add-On Treatment and Metabolites on Clock Gene Expression in Major Depression
Kathrin Kreuzer; Anna Maria Birkl-Toeglhofer; Johannes Haybaeck; Alexandra Reiter; Nina Dalkner; Frederike T Fellendorf; Alexander Maget; Martina Platzer; Matthias Seidl; Lilli-Marie Mendel; Melanie Lenger; Armin Birner; Robert Queissner; Marco Mairinger; Anna Obermayer; Alexandra Kohlhammer-Dohr; Tatjana Maria Stross; Alfred Häussl; Carlo Hamm; Helmut Schöggl; Daniela Amberger-Otti; Annamaria Painold; Theresa Lahousen-Luxenberger; Birgitta Leitner-Afschar; Tanja Färber; Sabrina Mörkl; Jolana Wagner-Skacel; Nathalie Meier-Allard; Sonja Lackner; Sandra Holasek; Hansjörg Habisch; Tobias Madl; Eva Reininghaus; Susanne Astrid Bengesser
2024
In plain language
In 53 adults with major depression, a 4 week probiotic supplement, which also contained vitamin B7, altered CLOCK gene expression in blood cells versus placebo, though B7 itself may have confounded the result.
- Evidence
- Established
- Design
- Randomized controlled trial
Cite this record: https://thecellwell.org/studies/HH-50674
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